Presumably a reference to the six Domínguez sisters – las hermanas means “the sisters” in Spanish – who had inherited this land, part of the enormous Rancho San Pedro, in 1883. Or at least it’s a reference to the two sisters with namesake streets nearby: Susana del Amo and Victoria Domínguez de Carson. The Domínguez heirs developed a 1,300 acre industrial site right here in 1954-1955, so this street could have been named as early as then, but the earliest mention I found was in 1968.
Find it on the map:
